Crisis on Infinite Earths #12 (1986)

"Final Crisis"

DC Comics' seminal event of the 1980s, "Crisis on Infinite Earths" spanned the entire canonical history of the DC Universe, from the beginning of time to the very near end of all and combined the myriad dimensions, characters, and timelines crafted through DC history into one seamless whole.  At least that was the plan, though the resulting continuity would be revisted several times in the next twenty years.  Nevertheless, the original Crisis storyline was truly epic in scope, a comics milestone, and, most importantly, tremendously entertaining.  The finale of this mini-series was issue #12, chronicling the climactic battle between the nihlistic Anti-Monitor and virtually all the DC Universe's heroes and villains.  Bringing to illustrated life Marv Wolfman's paradigm shift, George Perez, Jerry Ordway, and Tom Ziuko create iconic images, beginning with this memorable cover work.  Befitting the scope of the final chapter of this saga (the issue includes the first appearance of Wally West as the Flash and the deaths of Kole and Earth-2's Robin and Huntress, along with many more superbeings and thousands upon thousands of normal human beings), the cover conveys the enormity of the battle to be fought while showcasing a host of characters, some of which would never be seen again.